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Fluid Bed Processor, Fluidized Bed Processor – Top Spray Granulation Capacity available 5 Kg to 500 Kg batch for US FDA &  cGMP Project

Fluid Bed Top Spray Granulation Fluid Bed Equpment, Processor, Top Spray Granulation

Fluid Bed Top Spray Granulation , Fluid Bed Equipment, Processor, Top Spray Granulation Capacity available 5 Kg to 1000 Kg batch for US FDA &  cGMP Project

Different model customized we make  Fluid Bed Top Spray Granulation & Processor , Top & bottom spray Fluid Bed Systems , Top Spray Fluid Bed Granulation Machine , Fluidized Bed Multi-functional Processors  or   Fluid Bed Coating with Multifunctional Processors  , fluidized beds process with integrated top spraying for granulations and coatings, fluid bed processor with bottom spraying for coating, granulations, drying & pellets coating in one unit.

Fluid Bed Processing systems , Wurster Coaters , Fluidized Bed Coating and Granulating Systems

Fluid bed Processor, Fluid Bed Processing systems , Wurster Coaters , Fluidized Bed Coating and Granulating Systems

Features:

  • Fluid bed granulator & dryer , fluid bed processor design for spray granulation and pellet coating.
  • Coating Spray guns is easy to observed with adjusted.
  • The designs makes the coatings uniformity and high roundness, particle damage will not happen.
  • Easy to charging and discharges, meet FDA/cGMP requirement
  • Pellet coating procedures is faster than bottoms spray coating, less material loss..

The granulation chamber consists

  • Air Handling Unit (AHU) of Fluid Bed Processor
  • The Inlet Air Handling Unit Consists:
  • Pre-filter G4
  • Intermediate Filter F8
  • Wheel dehumidification
  • Base part
  • Movable product container(Include Top spray & Bottom spray, tangent spray as option item)
  • Expansion chamber
  • Filter chamber

USAGE:  Fluid Bed Dryer/Granulator/Coater Multi-Processor, Fluid bed Processor, Fluid bed Equipment

FBC Series Fluid-bed Multi-processor is added bottom spray on the base of FBG series Fluid-bed Granulator, thus can realize drying, granulating and bottom spray coating on one machine, and with function of mixing raw material, granulation, dying and coating for granules or pellets. The equipment is PLC auto controlled and well satisfies with the current GMP and the National Pharmacopoeia.

 

WORKING PRINCIPLE:

The intake air is processed from the inlet AHU through filters and heated, then lead into the lower bowl. The material is blow up evenly by hot air which passes through air distribution plate of product bowl, then forms continuous fluidized state and dried evenly by hot air.In case of top spray for f luidized granulation, use top spray movable product bowl, the binder is top sprayed through spray guns in diffuse chamber into the product bowl, and spray onto the material surface atomized by compressed air. The product granules cohere each other by the binder and get the binder bridge to form the core granules, then grow up to form required wet granules, which the binder dried evenly by hot air and finally get dry granules.

In case of bottom spray for coating, use bottom spray movable product bowl, the binder changes to spray from bottom spray guns and atomized. The granules or pellet sprayed from bottom to top inside of fluidized chamber and coated by coating solutions, then fall back along the wall of bottom spray product bowl and dried by hot air, which back to bottom are sprayed again from fluidized chamber and repeat coating process.

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INLET AHU

 

The inlet AHU including three stage filters with G4, F8 and H13, dehumidifier with surface cooler, inlet air temperature controlled by cold and hot air mixing door, inlet air volume by inverter controlled which can set and adjust.

MAIN BODY STRUCTURE

 

The main body structure consists of lower bowl, top spray movable product bowl, bottom spray movable product bowl, diffuse chamber and filter chamber. The lower bowl, movable product bowl and diffuse chamber are silicon inflatable sealed with compress air inspection to assure the reliable sealing.

PRODUCT FILTER

The pulse anti-blow filter clean device adopts anti-static cloth filter (in case request, stainless steel anti-blow filter is available), which is silicon inflatable sealed with the filter chamber with compress air inspection to assure the reliable sealing. A dust sensor is mounted on the exhaust piping and interlocked with PLC control sys to secure the product safety during production.

 

EXHAUST AHU

 

The exhaust dust collection sys can be optionally designed upon request to protect environment.

2 BAR & 10 BAR DUST EXPLOSION DESIGN

 

The 2 bar and 10 bar powder ex-proof design is selectable to ensure the operator, equipment and environment safety with reliable grounding device.

FLUIDZED GRANULATION

In case of fluidized granulation is requested, the binder solution tank and spray sys with peristaltic pump would be supplied. The binder sprays into product bowl through spray guns and spray onto the material surface atomized by compressed air. The product granules cohere each other by the binder and get the binder bridge to form the core granules, then grow up to form required wet granules, which the binder dried evenly by hot air and finally get dry granules.

BOTTOM SPRAY FOR COATING

 

In case of bottom spray for coating, use bottom spray movable product bowl, the binder changes to spray from bottom spray guns and atomized. The granules or pellet sprayed from bottom to top inside of fluidized chamber and coated by coating solutions, then fall back along the wall of bottom spray product bowl and dried by hot air, which back to bottom are sprayed again from fluidized chamber and repeat coating process. The height of fluidized chamber can be adjusted according to the quantity of material, and get the best fluid state. The bottom spray air distributing plate can be changed to different spray distance and flow based on material characteristics.

 

Fluid Bed Processor and Fluidized Bed Processor are versatile pieces of equipment widely used in the pharmaceutical, food, and chemical industries for processes such as drying, granulation, and coating. These machines provide efficient and controlled processing with the capability of performing multiple functions such as top spray granulation, coating, and drying in a single system.

Key Features and Applications of Fluid Bed Processor:

1. Fluid Bed Dryer/Granulator/Coater Multi-Processor:

  • Multi-functional: The Fluid Bed Processor acts as a dryer, granulator, and coater, which makes it a multi-purpose equipment capable of carrying out different processes in a single system.
  • Top Spray Granulation: This is one of the key processes performed by the Fluid Bed Processor. In top spray granulation, the material is sprayed from the top into the fluidized bed of powders or granules, which are subjected to heat and airflow. This process helps in granulating powders into larger particles that have improved flow properties, uniformity, and density.
  • Coating: The system also supports coating applications, where a coating material is sprayed onto the particles, making it ideal for film coating of granules or tablets, improving product aesthetics, taste masking, or controlled release properties.

2. Capacity and Batch Sizes:

  • Batch Sizes Available: The Fluid Bed Processor can handle batch sizes ranging from 5 kg to 500 kg, depending on the application and requirements.
    • 5 Kg to 20 Kg: Suitable for pilot scale or small-scale batch production.

    • 20 Kg to 1000 Kg: Ideal for larger commercial production with higher throughput.

  • Flexible Usage: The wide capacity range makes the system adaptable to both small-scale R&D and large-scale production, supporting various stages of product development and manufacturing.

3. US FDA & cGMP Compliance:

  • Compliance: The Fluid Bed Processor is built to meet stringent standards, including US FDA and cGMP (current Good Manufacturing Practices) guidelines, ensuring that the equipment is suitable for use in regulated industries like pharmaceuticals, nutraceuticals, and food.
  • Pharmaceutical Applications: These machines are commonly used in the pharmaceutical industry for the production of tablets, capsules, and granules, ensuring high-quality control and adherence to regulatory requirements.

4. Fluid Bed Processor Components and Technology:

  • Airflow System: The system is equipped with an adjustable airflow system, which is essential for controlling the fluidization of the particles and maintaining consistent heat distribution throughout the batch.
  • Spray System: The top spray granulation or coating process is achieved through a spray nozzle that atomizes the liquid binder or coating solution, ensuring uniform coating or granulation.
  • Heating and Drying: The system uses heated air for the drying process, efficiently removing moisture from the granules or powder.
  • Separation and Collection: The granules or particles are separated from the air using cyclonic separation or filtration systems and collected for further processing or packaging.

5. Applications:

  • Pharmaceutical Industry: The Fluid Bed Processor is widely used in granulation and coating processes for producing tablets, capsules, and granules with controlled release, taste masking, or stability-enhancing coatings.
  • Nutraceuticals: Used for producing granules or tablets with improved bioavailability and stability.
  • Food Industry: Used for granulating ingredients, coating snacks, or improving powder flowability.
  • Chemical Industry: Employed in the processing of various chemicals that require drying, granulation, or coating.

6. Advantages of Fluid Bed Processor:

  • Efficiency: The fluidization process ensures uniform heating and moisture removal, leading to faster drying times and consistent product quality.
  • Reduced Solvent Usage: With controlled spraying, the amount of solvent or binder used in granulation or coating is optimized, reducing waste and cost.
  • Scalability: The machine can easily scale from pilot production to large-scale manufacturing without compromising on performance or quality.
  • Enhanced Product Properties: Granulated particles produced via fluid bed granulation have better flowability, uniform particle size distribution, and improved compaction properties, which are ideal for tableting or encapsulation.
  • Compliance and Quality Assurance: Adheres to US FDA and cGMP standards, ensuring high-quality, safe, and regulatory-compliant production processes.

7. Fluid Bed Equipment Configuration:

  • Granulation System: For the production of granules from fine powders, ensuring better compaction and uniformity.
  • Drying System: Using hot air for drying moist granules or powders, ensuring the final product is free from excess moisture.
  • Coating System: For uniform coating of granules or tablets, ideal for controlled release or protective coatings.

Conclusion:

The Fluid Bed Processor from Shree Bhagwati Machtech is a versatile and essential piece of equipment for industries requiring controlled granulation, drying, and coating processes. It is especially valuable in the pharmaceutical, food, and chemical industries, where high-quality and efficient processing is critical. With a batch capacity range of 5 kg to 1000 kg, FDA and cGMP compliance, and the ability to handle multi-functional processes, the Fluid Bed Processor meets the needs of both small-scale R&D and large-scale commercial production. The technology ensures uniformity, consistency, and product quality, making it an ideal choice for companies focused on high-quality manufacturing.