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Granulation line – Batch Granulation Line – Integrated Granulation Line Equipment Manufacturer
Pharmaceutical granulator , Solid Preparation Granulating Line, automatic Granulating machine

Pharmaceutical granulator, Solid Preparation Granulating Line, automatic Granulating machine Pharmaceutical Integrated granulation line including High speed Mixer & Granulator, Inline Wet mill, Fluid Bed Dryer & Granulator, lifting device with Inline Dry Mill, and IBC Lift Blender at different sizes depending on customer demand.

SHREE BHAGWATI is a global leader in the design and manufacturing of automatic machinery used in the processing and packaging of pharmaceuticals products.

specialized experts with many years of experience in practice.

Pellet Production Customized Granulation Line

 

Granulation Isolators including a range of workstations including.

  • Granulators
  • Fluid Bed Dryers
  • Dry and Wet Mill
  • Blenders

Our Granulation isolators typically are offered in.

  • 2kg – 10kg

There are two types of Granulation Lines employed in the production of solid dosage forms in the Pharmaceutical Industry.

  • Wet Granulation
  • Dry Granulation

 

Granulation line under isolator high containment

Isolator For 5 Kgs Granulation Line,

Isolator For 5 Kgs Granulation Line,

Complete granulation lines for small batch production, mounted under isolator in high containment OEB 5. A line can be composed by a high shear mixer, fluid bed dryer (12-bar pressure resistant construction), cone mill to calibrate dry or wet products, possible kit for the transfer of the powder by vacuum, a washing and drying system. All systems have been designed to ensure maximum operator protection, during handling operations of products with high level of toxicity. The equipment is fully customizable based on client requests.

Isolator Granulation Line for Handling High Potent Products

 

 

Wet Granulation Line

SHREE BHAGWATI provides machines, equipment and barrier isolators for the wet granulation line including the Feed Station, Milling, Sieving, High Shear Mixing, Fluid Bed Processing and Blending. SHREE BHAGWATI has also fully integrated barrier isolator solutions for the Tablet Press Machine and Coating Machine and can supply turnkey solutions for Vacuum powder transfer systems powder and CIP / WIP systems.

 

The process of wet granulation involves the addition of a liquid solution to a powder mixture and the massing of the mix to produce granules. Typical liquids include water, ethanol and is propane and once the powders have formed into a dense mass and the granulation fluid has been evaporated then the granules are milled to an appropriate size for compression.

 

The extact process depends on the characteristics of the powders and the final dosage form. Organic solvents are used when water sensitive drugs are processed, as an alternative to dry granulation, or when a rapid drying time is required.

 

As direct compression is not the best technology for many active substances, wet granulation is still a preferred method. Even if the active substance is sensitive to hydrolysis, modern equipment such as a fluidized bed eliminates the problems associated with wet granulation. Products including anti-neo plastic agents/Hormones(OEB3) may be produced using wet granulation. Below shows an example of a 2kg Granulation Line Barrier Isolator including Rapid Mix Granulator (RMG), a Fluid Bed Dryer (FBD) and Multi-mill blender workstations, designed and manufactured by SHREE BHAGWATI.

 

Pharma Integrated Granulation Line

Solid Dose granulation line

Solid Dose granulation line Wet granulation remains the most widely used process for production of pharmaceutical solid-dosage forms.

 

SHREE BHAGWATI Pharmaceutical Integrated granulation line including High speed Mixer & Granulator, Inline Wet mill, Fluid Bed Dryer & Granulator, lifting device with Inline Dry Mill, and IBC Lift Blender for Pharmaceutical / Nutraceuticals / Herbal / Ayurvedic at different sizes depending on customer demand batch capacity 10, 30, 60, 100, 150, 250, 500 and 1000 Kg. Suitable for pharmaceuticalchemicalfood and cosmetic industries.

Solid Dosage Granulation Line 

Granulation line – 250 Kg Pharmaceutical , Nutraceutical

Closed loop Granulation line: Generating high quality granules while reducing manpower requirement and equipment management costs.

Granulation line multiprocess equipment – Several batches per shift with a filling range from 12 L to 2,200 L processable volume.

Shree Bhagwati GRANULATION LINE for solid dosage forms also called inline process, it includes High Shear Mixer, Fluid Bed Dryer, Fluid Bed Processor, Fluid Bed Granulator, Lifting Column, Conical Mill, Vacuum Conveying System, Blender, etc.

Granulation lines are designed for manufacturing granules by mixing and agglomeration of powders in high shear mixers and drying in fluid bed.

As a pioneer and leading granulation line manufacturer of premium processing technology systems with 30 years of experience in the development and manufacture of solids, continuous processing becomes more and more important in pharmaceutical, health product, food, fine chemical, and feed processing industry.

Capacity: 2 kg. to 1000 kgs Granulation Lines employed in the production of solid dosage forms in the Pharmaceutical Industry; Wet Granulation; Dry Granulation , .

OEB 4 level toxic material wet type granulation Line – It is suitable for the production of highly toxic, highly active, and highly allergenic solid drugs, and must reach containment OEB4 & OEB5 to minimize the hazards of the operators during the production process and the impact on the environment.

Application and batch wise different requirement we offer Granulation Line, wall mounted granulation line, closed granulation line, solid preparation production line, toxic material granulation line, closed granulation line, solid preparation production line, OEB 4 level high containment granulation line, Wall Mounted Granulation Line, High Containment Wet Type Granulation Line.

1. OEB 4 level for toxic material production
2. Bag-in-bag-out air exhaust system
3. cleaning nozzles inside the pipes
4. Fully closed production

 

Wet Granulation process has since ever a significant major impact on batch production of OSD forms. It provides a great contribution to solve or mitigate issues related to the characteristics of the raw materials and ensure reliable and higher quality of the final product